Equitable machine learning counteracts ancestral bias in precision medicine
Abstract Gold standard genomic datasets severely under-represent non-European populations, leading to inequities and a limited understanding of human disease. Therapeutics…
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Comprehensive Investigation of a Tyrosine Kinase Inhibitor-Resistant Gene Zeste White 10 in Hepatocellular Carcinoma
Abstract Background: Tyrosine kinase inhibitors (TKIs) are first-line therapies for hepatocellular carcinoma (HCC), but the drug resistance restricts the long-term…
Subjective responses to simultaneous alcohol and cannabis use relative to alcohol‐only use and cannabis‐only use: An ecological momentary assessment investigation
Abstract Background: Few studies have examined subjective responses to simultaneous alcohol and cannabis use in naturalistic settings. The current study…
CB1 cannabinoid receptor agonists induce acute respiratory depression in awake mice☆
Abstract Recreational use of synthetic cannabinoid agonists (i.e., “spice compounds”) that target the cannabinoid type 1 receptor (CB1) can cause…
Comprehensive analysis of TMEM9 in human tumors
Abstract Background: TMEM9, a transmembrane protein, has emerged as a significant player in tumor progression, yet its comprehensive role across…
FN1 Immunoregulation in Glioblastoma: Insights From Neutrophil‐Centric Studies
Abstract Neutrophils, as key components of the tumor microenvironment, play a crucial role in cancer progression and prognosis. This study…
Pan‑cancer analysis of oncogene SFXN1 to identify its prognostic and immunological roles in lung adenocarcinoma
Abstract As cancer incidence and mortality rates continue to rise, the urgency for research in this field has increased globally.…
Diagnostic, prognostic, and immunological roles of NCAPG in pan-cancer: A bioinformatics analysis
Abstract Growing studies have shown that non-SMC condensin I complex subunit G (NCAPG) was highly expressed in a variety of…
Value of cannabidiol as adjunctive treatment for Lennox Gastaut syndrome: cost-effectiveness and budget impact analysis
Abstract Background: Lennox-Gastaut syndrome (LGS) is a severe encephalopathic disease that leads to a decrease in the quality of life,…
Phytochemical Profile and Anticancer Activity of Achillea conferta Leaf Extracts: Insights Into Antioxidant Properties
Abstract This study explores the phytochemical composition and biological potential of extracts from Achillea conferta leaves, specifically hydroethanolic extract (HE),…