Beliefs and perceived benefits and harms of perinatal cannabis use among pre- and post-pregnancy women
Abstract Background: Cannabis use in pregnancy is increasing, despite evidence linking perinatal cannabis use (PCU) to maternal and infant health…
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Advances in Atopic Dermatitis Treatment: From Pathogenesis to Natural Product‐Based Therapies
Abstract Atopic dermatitis (AD), a widespread and chronic inflammatory skin disorder, profoundly affects patients’ quality of life, imposes significant psychological…
Potential of Cannabidiol (CBD) to overcome extensively drug-resistant Acinetobacter baumannii
Abstract Supplementary Information: The online version contains supplementary material available at 10.1186/s12906-025-05056-w. Article type: Research Article Keywords: Antimicrobial resistant, Cannabidiol,…
Palmitoylethanolamide in the Treatment of Pain and Its Clinical Application Prospects
Abstract Palmitoylethanolamide (PEA) has attracted increasing attention from researchers as an endogenous lipid mediator. It exhibits a unique mechanism of…
Investigation of the combined effects of cannabidiol plus naltrexone on alcohol craving in alcohol dependence: study protocol of a phase II randomised, double-blind, placebo-controlled, parallel-group trial – ICONICplus Trial
Abstract Introduction: Alcohol dependence (AD) is highly prevalent and has severe consequences on health and quality of life. However, the…
Effects of cannabidiol to circadian period, sleep, life span, close-proximity rhythm, egg reproduction and motor function in Drosophila melanogaster
Abstract Cannabidiol (CBD), a non-psychoactive cannabinoid, has been studied for its various health-promoting effects recently. This study investigates the effects…
α‑Glucosidase Inhibitors from the Leaves of Cannabis sativa: Structure–Activity Relationship, Kinetic Investigation, and Molecular Docking
Abstract Cannabis sativa L. is a valuable agricultural crop, extensively utilized in various fields and comprising diverse chemical constituents. In…
Pharmacological advances in cannabinoid-based therapies for pancreatic cancer: preclinical efficacy of CCL-106 and its epimers
Abstract Background: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive and lethal form of cancer with limited treatment options and poor…
TRP channels in hepatocellular carcinoma: integrative Mendelian randomization and multi-omics analyses highlight MCOLN3/TRPV4 as candidate dual-effect biomarkers
Abstract Background: The causal relationship between Transient receptor potential (TRP) and hepatocellular carcinoma (HCC) remains unclear. Our study aimed to…
Clinically Meaningful Reduction in Drop Seizures in Patients with Lennox–Gastaut Syndrome Treated with Cannabidiol: Post Hoc Analysis of Phase 3 Clinical Trials
Abstract Background and Objective: In clinical trials of patients with Lennox–Gastaut syndrome (LGS), a ≥ 50% reduction in drop seizure…