Use of alcohol and drugs by Norwegian employees: a pilot study using questionnaires and analysis of oral fluid
Abstract Background: The use of alcohol and drugs may affect workplace safety and productivity. Little is known about the magnitude…
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Nutritional interventions in the anorexia of aging
Keywords: Nursing Home Resident, Nutritional Intake, Dronabinol, Oral Nutritional Supplement, Good Nutritional Status Authors: L.M. Donini, C. Savina, C. Cannella…
Molecular Mechanisms Involved in the Antitumor Activity of Cannabinoids on Gliomas: Role for Oxidative Stress
Abstract Cannabinoids, the active components of Cannabis sativa, have been shown to exert antiproliferative and proapoptotic effects on a wide…
Cannabidiol Attenuates the Appetitive Effects of Δ9-Tetrahydrocannabinol in Humans Smoking Their Chosen Cannabis
Abstract Worldwide cannabis dependence is increasing, as is the concentration of Δ9-tetrahydrocannabinol (THC) in street cannabis. At the same time,…
Exploiting Nanotechnologies and TRPV1 Channels to Investigate the Putative Anandamide Membrane Transporter
Abstract Background: Considerable efforts have been made to characterize the pathways regulating the extracellular levels of the endocannabinoid anandamide. However,…
The cardiac and haemostatic effects of dietary hempseed
Abstract Despite its use in our diet for hundreds of years, hempseed has surprisingly little research published on its physiological…
INCANT: a transnational randomized trial of Multidimensional Family Therapy versus treatment as usual for adolescents with cannabis use disorder
Abstract Background: In 2003, the governments of Belgium, France, Germany, the Netherlands and Switzerland agreed that there was a need…
FAAH−/− Mice Display Differential Tolerance, Dependence, and Cannabinoid Receptor Adaptation After Δ9-Tetrahydrocannabinol and Anandamide Administration
Abstract Repeated administration of Δ9-tetrahydrocannabinol (THC), the primary psychoactive constituent of Cannabis sativa, induces profound tolerance that correlates with desensitization…
N-arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor
Abstract Background: Microglia provide continuous immune surveillance of the CNS and upon activation rapidly change phenotype to express receptors that…
Cross-national differences in clinically significant cannabis problems: epidemiologic evidence from ‘cannabis-only’ smokers in the United States, Mexico, and Colombia
Abstract Background: Epidemiological studies show wide variability in the occurrence of cannabis smoking and related disorders across countries. This study…