Cross-national differences in clinically significant cannabis problems: epidemiologic evidence from ‘cannabis-only’ smokers in the United States, Mexico, and Colombia

Abstract Background: Epidemiological studies show wide variability in the occurrence of cannabis smoking and related disorders across countries. This study aims to estimate cross-national variation in cannabis users’ experience of clinically significant cannabis-related problems in three countries of the Americas, with a focus on cannabis users who may have tried alcohol or tobacco, but who have not used cocaine, heroin, LSD, or other internationally regulated drugs. Methods: Data are from the World Mental Health Surveys Initiative and the National Latino