Pan-cancer analysis of the prognostic and immunological role of matrix metalloproteinase 9
Abstract Matrix metalloproteinase 9 (MMP9), a zinc ion-dependent endopeptidase, is one of the most complex matrix metalloproteinases in the gelatinase…
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SHP2 is involved in the occurrence, development and prognosis of cancer
Abstract Src homology-2 domain-containing protein tyrosine phosphatase (SHP2), encoded by protein tyrosine phosphatase non-receptor type 11 (PTPN11), is widely expressed…
International perspective on physician knowledge, attitude and practices related to medical cannabis
Abstract Background: The trends of recreational use of cannabis and use of cannabis for medical indications (i.e. “medical cannabis”) have…
In Silico Discovery and Subsequent Characterization of Potent 4R-Tauopathy Positron Emission Tomography Radiotracers
Abstract A chemical fingerprint search identified Z3777013540 (1-(5-(6-fluoro-1H-indol-2-yl)pyrimidin-2-yl)piperidin-4-ol; 1) as a potential 4R-tau binding ligand. Binding assays in post-mortem Alzheimer’s…
Social Stigma and Discrimination Toward People With Drug Addiction: A National Survey in Korea
Abstract Objective: This study aims to understand the attitudes, stigma, and discrimination of the general adult population toward drug addiction.…
Dataset for developing optimal headway-based bus dispatching strategy during epidemic outbreaks
Abstract This article presents the data utilized in a study focused on identifying an optimal bus dispatching strategy in light…
SLC17A9 expression levels in a pan‑cancer panel and validation of the role of SLC17A9 as a novel prognostic biomarker for osteosarcoma
Abstract Previous studies have demonstrated the involvement of the solute carrier family 17 member 9 (SLC17A9) in certain types of…
MicroRNA-335-5p suppresses voltage-gated sodium channel expression and may be a target for seizure control
Abstract Despite the clinical availability of over 30 antiseizure medications, around 30% of people with epilepsy do not achieve seizure…
Cannabis use among workers with work-related injuries and illnesses: results from a cross-sectional study of workers’ compensation claimants in Ontario, Canada
Abstract Objectives: Little is known about how workers use cannabis following a work-related injury/illness, including whether they receive clinical guidance.…
Caregivers’ Perspectives on the Impact of Cannabidiol (CBD) Treatment for Dravet and Lennox-Gastaut Syndromes: A Multinational Qualitative Study
Abstract Objective: To increase understanding of the impact of cannabidiol (CBD) on outcomes beyond seizure control among individuals with Dravet…