Pan-cancer analyses reveal GTSE1 as a biomarker for the immunosuppressive tumor microenvironment
Abstract G2 and S phase-expressed-1 (GTSE1) has been reported to be associated with poor prognosis in many cancer types. However,…
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Unique epitope–antibody interactions in the intrinsically disordered proteoglycan-like domain of human carbonic anhydrase IX defined by high-resolution NMR combined with yeast surface display
Abstract Carbonic anhydrase (CA)-IX is an extracellular enzyme that is essential in the adaptation of tumor cells to their increasingly…
Association between chronic disease and substance use among older adults in Tennessee
Abstract Background: Substance use and misuse have a negative impact on health care outcomes, specifically in the older adult population.…
Cannabinol (CBN; 30 and 300 mg) effects on sleep and next-day function in insomnia disorder (‘CUPID’ study): protocol for a randomised, double-blind, placebo-controlled, cross-over, three-arm, proof-of-concept trial
Abstract Objective: Insomnia is the most prevalent sleep disorder, with few effective pharmacotherapies. Anecdotal reports and recent preclinical research suggest…
Comprehensive Analysis of CdS Ultrathin Films Modified by the Substrate Position inside the Reactor Container Using the CBD Technique
Abstract The cadmium sulfide (CdS) n-type semiconductor is one of the most used as a window layer in thin-film solar…
A statewide study of disparities in local policies and tobacco, vape, and cannabis retail environments
Abstract Policy strength was associated with jurisdiction sociodemographic composition. For tobacco and vape, policy strength was not associated with retailer…
Comparing [3H] thymidine LPT and CFSE assay to assess lymphocyte proliferation in beryllium-exposed sarcoidosis patients
Abstract The detection of antigen specific lymphocyte responses plays a vital role in the diagnosis of various diseases. Beryllium-specific [3H]…
Retrospective chart review of substance abuse in patients with psychiatric emergencies in an emerging urban county
Abstract Objectives: Substance abuse is common in patients with psychiatric emergencies. To further understand the connection between substance abuse and…
Inferring chromosomal instability from copy number aberrations as a measure of chromosomal instability across human cancers
Abstract Background: Cancer is a complex disease that is the second leading cause of death in the United States. Despite…
On the role of functional groups in the formation of diazonium based covalent attachments: dendritic vs. layer-by-layer growth†
Abstract Multilayered growth is often observed upon electrografting aryl diazonium derivatives on graphitic substrates due to the reactive nature of…