The Effects of Stigma: Older Persons and Medicinal Cannabis
Abstract Cannabis has long been stigmatized as an illicit drug. Since legalization in Canada for both medical and recreational purposes,…
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Reassortments in single-stranded DNA multipartite viruses: Confronting expectations based on molecular constraints with field observations
Abstract Single-stranded DNA multipartite viruses, which mostly consist of members of the genus Begomovirus, family Geminiviridae, and all members of…
Cannabidiol reduces intraventricular hemorrhage brain damage, preserving myelination and preventing blood brain barrier dysfunction in immature rats
Abstract Intraventricular hemorrhage (IVH) is an important cause of long-term disability in extremely preterm infants, with no current treatment. This…
The synthetic cannabinoid 5-fluoro ABICA upregulates angiogenic markers and stimulates tube formation in human brain microvascular endothelial cells
Abstract Objective: Synthetic cannabinoids (SCs), a class of psychoactive compounds emulating the effects of natural cannabis, have prompted addiction and…
Assessing Dose- and Sex-Dependent Antinociceptive Effects of Cannabidiol and Amitriptyline, Alone and in Combination, and Exploring Mechanism of Action Involving Serotonin 1A Receptors
Abstract SIGNIFICANCE STATEMENT: Inflammatory pain is an important component of both acute and chronic pain. We have found that cannabidiol…
NF2 is a candidate diagnosis, prognostic, and immunotherapeutic biomarker: a systematic pan-cancer analysis
Abstract Background: Neurofibromin 2 (NF2) regulates diverse cellular events such as transcription, translation, ubiquitination, and micro-RNA biosynthesis. Previous evidence revealed…
Cannabis use among cancer patients and survivors in the United States: a systematic review
Abstract Background: How cannabis products are being used by cancer patients and survivors in the United States is poorly understood.…
A pancancer analysis of histone deacetylase 3 in human tumors
Abstract Background: Histone deacetylase 3 (HDAC3) is known to be an important role in various kinds of cancer, but its…
Partially substituting alfalfa hay with hemp forage in the diet of goats improved feed efficiency, ruminal fermentation pattern and microbial profiles
Abstract The use of hemp as a forage source in livestock diets has been less studied because bioactive residues in…
Pan-cancer analysis of ABCC1 as a potential prognostic and immunological biomarker
Abstract ABCC1 expression exhibited intricate associations with diverse immune-related genes. ScRNA-seq analysis from GEO revealed a positive correlation between ABCC1…