A role for intestinal TLR4-driven inflammatory response during activity-based anorexia
Abstract Anorexia nervosa (AN) is associated with low-grade systemic inflammation and altered gut microbiota. However, the molecular origin of the…
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A randomised controlled trial of the clinical and cost-effectiveness of a contingency management intervention compared to treatment as usual for reduction of cannabis use and of relapse in early psychosis (CIRCLE): a study protocol for a randomised controlled trial
Abstract Background: Around 35–45 % of people in contact with services for a first episode of psychosis are using cannabis.…
Effect of cannabis smoking on lung function and respiratory symptoms: a structured literature review
Abstract As cannabis use increases, physicians need to be familiar with the effects of both cannabis and tobacco on the…
A Personal Retrospective: Elevating Anandamide (AEA) by Targeting Fatty Acid Amide Hydrolase (FAAH) and the Fatty Acid Binding Proteins (FABPs)
Abstract This perspective was adapted from a Career Achievement Award talk given at the International Cannabinoid Research Society Symposium in…
Splendor in the Grass? A Pilot Study Assessing the Impact of Medical Marijuana on Executive Function
Abstract Currently, 25 states and Washington DC have enacted full medical marijuana (MMJ) programs while 18 states allow limited access…
Disease Monitoring and Health Campaign Evaluation Using Google Search Activities for HIV and AIDS, Stroke, Colorectal Cancer, and Marijuana Use in Canada: A Retrospective Observational Study
Abstract Background: Infodemiology can offer practical and feasible health research applications through the practice of studying information available on the…
Preclinical and Clinical Assessment of Cannabinoids as Anti-Cancer Agents
Abstract Cancer is the second leading cause of death in the United States with 1.7 million new cases estimated to…
Metagenomic analysis of medicinal Cannabis samples; pathogenic bacteria, toxigenic fungi, and beneficial microbes grow in culture-based yeast and mold tests
Abstract Background: The presence of bacteria and fungi in medicinal or recreational Cannabis poses a potential threat to consumers if…
An Orally Active Cannabis Extract with High Content in Cannabidiol attenuates Chemically-induced Intestinal Inflammation and Hypermotility in the Mouse
Abstract Anecdotal and scientific evidence suggests that Cannabis use may be beneficial in inflammatory bowel disease (IBD) patients. Here, we…
Δ9-THC Intoxication by Cannabidiol-Enriched Cannabis Extract in Two Children with Refractory Epilepsy: Full Remission after Switching to Purified Cannabidiol
Abstract Animal studies and preliminary clinical trials have shown that cannabidiol (CBD)-enriched extracts may have beneficial effects for children with…