Development of [18F]LU14 for PET Imaging of Cannabinoid Receptor Type 2 in the Brain
Abstract Cannabinoid receptors type 2 (CB2R) represent an attractive therapeutic target for neurodegenerative diseases and cancer. Aiming at the development…
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Phytochemicals in Cancer Immune Checkpoint Inhibitor Therapy
Abstract The interaction of immune checkpoint molecules in the tumor microenvironment reduces the anti-tumor immune response by suppressing the recognition…
The Effect of Hemp (Cannabis sativa L.) Seeds and Hemp Seed Oil on Vascular Dysfunction in Obese Male Zucker Rats
Abstract Seeds of industrial hemp (Cannabis sativa L.) contain a large amount of protein (26.3%), dietary fiber (27.5%), and fatty…
Cannabinoids, their cellular receptors, and effects on the invasive phenotype of carcinoma and metastasis
Abstract Background: The morbidity and mortality of cancer are significantly impacted by the invasive and metastatic potential of particular subgroups…
Use and caregiver-reported efficacy of medical cannabis in children and adolescents in Switzerland
Abstract Supplementary information: The online version contains supplementary material available at 10.1007/s00431-021-04202-z. Article type: Research Article Keywords: Medical cannabis, Cannabidiol,…
French recommendations for the management of systemic sclerosis
Abstract Systemic sclerosis (SSc) is a generalized disease of the connective tissue, arterioles, and microvessels, characterized by the appearance of…
The use and effects of synthetic cannabinoid receptor agonists by New South Wales cannabis treatment clients
Abstract Introduction: Despite decreasing consumption by general populations, use of synthetic cannabinoid receptor agonists (SCRAs) persists in some marginalised groups,…
Cannabinoids Accumulation in Hemp (Cannabis sativa L.) Plants under LED Light Spectra and Their Discrete Role as a Stress Marker
Abstract Simple Summary: Cannabinoids accumulation in the hemp plant greatly depends on light quality under a controlled growing system. Sativa-type…
Targeting the Endocannabinoid System in the Treatment of Posttraumatic Stress Disorder: A Promising Case of Preclinical-Clinical Translation?
Abstract The endocannabinoid (eCB) system is one the most ubiquitous signaling systems of the brain and offers a rich pharmacology…
The Impact of THC and CBD in Schizophrenia: A Systematic Review
Abstract Background: People with schizophrenia are more likely to develop cannabis use disorder (CUD) and experience worse outcomes with use.…