Genotoxicity of Marijuana in Mono-Users
Abstract Marijuana (Cannabis sp.) is among the most recurred controlled substances in the world, and there is a growing tendency…
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Reviewing the Role of the Endocannabinoid System in the Pathophysiology of Depression
Abstract Major depressive disorder is a high-impact, debilitating disease and it is currently considered the most prevalent mental illness. It…
Strain-, Sex-, and Time-Dependent Antidepressant-like Effects of Cannabidiol
Abstract Cannabidiol (CBD) is a non-intoxicating compound extracted from Cannabis sativa, showing antidepressant-like effects in different rodent models. However, inconsistent…
Efficacy and safety of medical cannabinoids in children: a systematic review and meta-analysis
Abstract Despite the increased use of medical cannabinoids, the efficacy and safety of the treatment among children remain uncertain. The…
Mechanical characteristics of bacterial cellulose-reinforced mycelium composite materials
Abstract Background: While mycelium is considered a promising alternative for fossil-based resins in lignocellulosic materials, the mechanical properties of mycelium…
Inflammatory Biomarkers in Addictive Disorders
Abstract Substance use disorders are a group of diseases that are associated with social, professional, and family impairment and that…
Antiseizure Effects of Fully Characterized Non-Psychoactive Cannabis sativa L. Extracts in the Repeated 6-Hz Corneal Stimulation Test
Abstract Compounds present in Cannabis sativa L. preparations have recently attracted much attention in the treatment of drug-resistant epilepsy. Here,…
Clinical Investigation on the Impact of Cannabis Abuse on Thyroid Hormones and Associated Psychiatric Manifestations in the Male Population
Abstract Cannabis abuse is a common public health issue and may lead to considerable adverse effects. Along with other effects,…
The Effect of Marijuana on the Incidence and Evolution of Male Infertility: A Systematic Review
Abstract Over the past decade, the consumption of marijuana or any other form of cannabis, whether medically, recreationally, or illegally,…
Endocannabinoid System and Tumour Microenvironment: New Intertwined Connections for Anticancer Approaches
Abstract The tumour microenvironment (TME) is now recognised as a hallmark of cancer, since tumour:stroma crosstalk supports the key steps…