Molecular Alterations of the Endocannabinoid System in Psychiatric Disorders
Abstract The therapeutic benefits of the current medications for patients with psychiatric disorders contrast with a great variety of adverse…
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Hempseed (Cannabis sativa) Peptide H3 (IGFLIIWV) Exerts Cholesterol-Lowering Effects in Human Hepatic Cell Line
Abstract Hempseed (Cannabis sativa) protein is an important source of bioactive peptides. H3 (IGFLIIWV), a transepithelial transported intestinal peptide obtained…
Influence of Manufacturing Conditions on Binder-Less Boards from Steam-Exploded Hemp Shives and Wheat Straw
Abstract In the current decade, based on the European Green Deal, new challenges of the wood-based panel industry have arisen,…
Parkinson’s Disease and SARS-CoV-2 Infection: Particularities of Molecular and Cellular Mechanisms Regarding Pathogenesis and Treatment
Abstract Accumulating data suggest that chronic neuroinflammation-mediated neurodegeneration is a significant contributing factor for progressive neuronal and glial cell death…
Cannabis for Medical Use: Versatile Plant Rather Than a Single Drug
Abstract Medical Cannabis and its major cannabinoids (−)-trans-Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD) are gaining momentum for various medical purposes as…
Abuse of Non-opioid Analgesics in Germany: Prevalence and Associations Among Self-Medicated Users
Abstract Background: Abuse of non-opioid analgesics (NOA) is associated with serious health consequences. However, due to inconsistent definitions of NOA…
2′,3′,4′-Trihydroxychalcone changes estrogen receptor α regulation of genes and breast cancer cell proliferation by a reprogramming mechanism
Abstract Background: Menopausal hormone therapy (MHT) is recommended for only five years to treat vasomotor symptoms and vulvovaginal atrophy because…
Inflammation-targeted cannabidiol-loaded nanomicelles for enhanced oral mucositis treatment
Abstract One of the most common complications of cancer chemotherapy is oral mucositis (OM), a serious kind of oral ulceration,…
Molecular Mechanisms and Current Treatment Options for Cancer Cachexia
Abstract Simple Summary: The primary characteristics of cancer cachexia are weakness, weight loss, atrophy, fat reduction, and systemic inflammation. Cachexia…
Opioid-sparing effect of cannabinoids for analgesia: an updated systematic review and meta-analysis of preclinical and clinical studies
Abstract Cannabinoid co-administration may enable reduced opioid doses for analgesia. This updated systematic review on the opioid-sparing effects of cannabinoids…