New Psychoactive Substances Consumption in Opioid-Use Disorder Patients
Abstract Simple Summary: We applied a toxicological screening on 187 urine samples collected from patients with opioid-use disorder treated with…
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The acute effects of cannabidiol on emotional processing and anxiety: a neurocognitive imaging study
Abstract Rationale: There is growing interest in the therapeutic potential of cannabidiol (CBD) across a range of psychiatric disorders. CBD…
Validity of self-report measures of cannabis use compared to biological samples among women of reproductive age: a scoping review
Abstract Background: Most existing evidence about the prevalence of prenatal cannabis use relies on self-reported measures, which is limited by…
Modulation of Morphine Analgesia, Antinociceptive Tolerance, and Mu-Opioid Receptor Binding by the Cannabinoid CB2 Receptor Agonist O-1966
Abstract Acutely, non-selective cannabinoid (CB) agonists have been shown to increase morphine antinociceptive effects, and we and others have also…
Medicinal Cannabis and Central Nervous System Disorders
Abstract Cannabinoids, including those found in cannabis, have shown promise as potential therapeutics for numerous health issues, including pathological pain…
Recent Advances in Biocatalysis for Drug Synthesis
Abstract Biocatalysis is constantly providing novel options for the synthesis of active pharmaceutical ingredients (APIs). In addition to drug development…
Cannabis sativa CBD Extract Shows Promising Antibacterial Activity against Salmonella typhimurium and S. newington
Abstract Products derived from Cannabis sativa L. have gained increased interest and popularity. As these products become common amongst the…
TRPA1 Role in Inflammatory Disorders: What Is Known So Far?
Abstract The transient receptor potential ankyrin 1 (TRPA1), a member of the TRP superfamily of channels, is primarily localized in…
Impact of the Aversive Effects of Drugs on Their Use and Abuse
Abstract Drug use and abuse are complex issues in that the basis of each may involve different determinants and consequences,…
Cannabinoids Alleviate the LPS-Induced Cytokine Storm via Attenuating NLRP3 Inflammasome Signaling and TYK2-Mediated STAT3 Signaling Pathways In Vitro
Abstract Cannabinoids, mainly cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC), are the most studied group of compounds obtained from Cannabis sativa because…