Cannabidiol Increases Seizure Resistance and Improves Behavior in an Scn8a Mouse Model
Abstract Voltage-gated sodium channel genes are an important family of human epilepsy genes. De novo missense mutations in SCN8A (encoding…
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Berberine Alleviate Cisplatin-Induced Peripheral Neuropathy by Modulating Inflammation Signal via TRPV1
Abstract Chemotherapy induced peripheral neuropathy (CIPN) is a severe neurodegenerative disorder caused by chemotherapy drugs. Berberine is a natural monomer…
Tobacco Rattle Virus as a Tool for Rapid Reverse-Genetics Screens and Analysis of Gene Function in Cannabis sativa L.
Abstract Medical cannabis (Cannabis sativa L.) is quickly becoming a central agricultural crop as its production has continued to increase…
Driving Performance and Cannabis Users’ Perception of Safety
Abstract This randomized clinical trial studies the magnitude and time course of effects of cannabis on driving, effect of cannabis…
Industry-Based Misconceptions Regarding Cross-Pollination of Cannabis spp.
Abstract Cross-pollination of commercial crops has been an ongoing issue in many species. Cannabis spp. encompasses the classifications of marijuana…
Determination of Prenatal Substance Exposure Using Meconium and Orbitrap Mass Spectrometry
Abstract The aim of this study was to develop and to validate a toxicological untargeted screening relying on LC-HRMS in…
Treatment of Glaucoma with Natural Products and Their Mechanism of Action: An Update
Abstract Glaucoma is one of the leading causes of irreversible blindness. It is generally caused by increased intraocular pressure, which…
Characterisation of Hemp Fibres Reinforced Composites Using Thermoplastic Polymers as Matrices
Abstract Hemp fibres used as a reinforcing agent and three polymeric matrices (polypropylene, bicomponent, recycled polyester) were used to obtain…
Polysubstance Use Patterns Among High Dose Benzodiazepine Users: A Latent Class Analysis and Differences Between Male and Female Use
Abstract Benzodiazepines (BZDs) represent one of the most widely used groups of pharmaceuticals, but if used for long periods of…
Metabolomic Fingerprint of Behavioral Changes in Response to Full-Spectrum Cannabis Extracts
Abstract Numerous existing full-spectrum cannabis extract products have been used in clinical trials for the treatment of various diseases. Despite…