Bone Targeted Parathyroid Hormone Antagonists for Prevention of Breast Cancer Bone Metastases
Abstract Breast cancer frequently spreads to the bones, leading to pain, fractures, and other bone-related complications. Current treatments slow the…
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The Potential of Hair Matrix for Biomarker Analysis in Schizophrenia
Abstract Schizophrenia (SCZ) is a complex psychiatric disorder with positive, negative, and cognitive symptoms that cause long-term functional impairment. Despite…
Impact of Trainee Involvement on Outcomes in Acute Cholangitis: A Propensity-Matched Study in U.S. Hospitals
Abstract Introduction: This study analyzed the outcomes of acute cholangitis (AC) in teaching hospitals, comparing July-September (new trainees) to April-June…
Lipids from Oilcakes—High Quality Ingredients for Functional Food Products
Abstract Fatty acids (FAs) are vital for human nutrition and are classified into three categories (saturated, unsaturated, and trans). FAs…
Cannabinoids in Chronic Pain: Clinical Outcomes, Adverse Effects and Legal Challenges
Abstract Cannabinoids have gained increasing attention as potential therapeutic agents in chronic pain management. Their mechanisms of action, mediated through…
Progress in genetic mechanisms and precise treatment of neurocutaneous syndrome-related epilepsy
Abstract Neurocutaneous syndromes are a group of genetic disorders involving the nervous and cutaneous systems, including Tuberous Sclerosis Complex (TSC),…
Genetic Diversity and Disease Resistance Genes Profiling in Cultivated Coffea canephora Genotypes via Molecular Markers
Abstract Knowledge of the genetic diversity and resistance genes of Coffea canephora genotypes is essential to identify genetic resources that…
Cannabinoid Receptor 2 (CB2) in Macrophages: A Promising Clinical Target for Immune Disorders
Abstract Macrophages are essential for immune homeostasis, playing crucial roles in immune responses from initiation to resolution. They trigger acute…
Molecular pathogenesis of Alzheimer’s disease onset in a mouse model: effects of cannabidiol treatment
Abstract Introduction: Alzheimer’s disease (AD) is a common neurodegenerative condition involving a complex blend of disturbances in synaptic development and…
Design, Synthesis, and Molecular Docking of Triazole‐Coumarin Hybrids as Potent Breast Cancer Inhibitors Targeting Cell Cycle and Apoptosis
Abstract Breast cancer continues to pose a significant global health burden, highlighting the urgent need for novel chemotherapeutic agents with…