Cannabinoids in Chronic Pain: Clinical Outcomes, Adverse Effects and Legal Challenges
Abstract Cannabinoids have gained increasing attention as potential therapeutic agents in chronic pain management. Their mechanisms of action, mediated through…
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Progress in genetic mechanisms and precise treatment of neurocutaneous syndrome-related epilepsy
Abstract Neurocutaneous syndromes are a group of genetic disorders involving the nervous and cutaneous systems, including Tuberous Sclerosis Complex (TSC),…
Practical approach to the safe use of cannabidiol in patients with refractory epilepsy: a mini review
Abstract Drug-resistant epilepsy (DRE), characterized by seizures that are unresponsive to the use of two or more conventional anti-seizure medication…
CD93 in Health and Disease: Bridging Physiological Functions and Clinical Applications
Abstract CD93 is a highly glycosylated transmembrane glycoprotein with key functional domains, including a C-type lectin-like domain (CTLD) and epidermal…
A Meta-Narrative Review of Channelopathies and Cannabis: Mechanistic, Epidemiologic, and Forensic Insights into Arrhythmia and Sudden Cardiac Death
Abstract Although cannabinoids have proven therapeutic benefits, they are increasingly known for their capacity to disturb cardiac electrophysiology, particularly in…
Impact of Electron Beam Treatment and Storage Duration on Microbial Stability and Phytochemical Integrity in Hemp Flowers
Abstract This study compared the effects of storage time and electron beam (EB) irradiation on microbial counts and chemical stability…
Youth vaping prevention with urban Indigenous communities of the southwest U.S.: a protocol for a randomized controlled trial
Abstract Background: Indigenous adolescents have the highest rates of nicotine vaping and tend to initiate at an earlier age compared…
Cannabis use in adolescence and young adulthood and its effects on brain structure and function: a scoping review
Abstract Introduction: Adolescence and young adulthood are simultaneously periods of significant brain development and the ages in which people often…
Chemical Composition and Antioxidant Activity of the Stembark Essential Oils of Two Cannabis sativa L. Cultivars from Komga, South Africa
Abstract Cannabis sativa L. is an aromatic medicinal plant with various biologically active classes of compounds such as cannabinoids, polyphenols,…
Reproducible single-cell annotation of programs underlying T cell subsets, activation states and functions
Abstract T cells recognize antigens and induce specialized gene expression programs (GEPs), enabling functions like proliferation, cytotoxicity and cytokine production.…