Medicinal Cannabis for Paediatric Developmental, Behavioural and Mental Health Disorders
Abstract Parents of children with developmental, behavioural and mental health disorders are increasingly asking whether medicinal cannabis might be a…
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Pharmacological Modulation of Temporal Discounting: A Systematic Review
Abstract Temporal discounting is a phenomenon where a reward loses its value as a function of time (e.g., a reward…
Natural Cannabichromene (CBC) Shows Distinct Scalemicity Grades and Enantiomeric Dominance in Cannabis sativa Strains
Abstract Cannabichromene (CBC, 1a) occurs in Cannabis (Cannabis sativa) as a scalemate having a composition that is strain-dependent in terms…
The Cannabinoids, CBDA and THCA, Rescue Memory Deficits and Reduce Amyloid-Beta and Tau Pathology in an Alzheimer’s Disease-like Mouse Model
Abstract Most studies related to hemp are focused on Cannabidiol (CBD) and Tetrahydrocannabinol (THC); however, up to 120 types of…
The Polypharmacological Effects of Cannabidiol
Abstract Cannabidiol (CBD) is a major phytocannabinoid present in Cannabis sativa (Linneo, 1753). This naturally occurring secondary metabolite does not…
A Case of a Patient With Cannabis Hyperemesis Syndrome Along With Recurrent Nephrolithiasis
Abstract Cannabis hyperemesis syndrome (CHS) is a condition characterized by cyclic vomiting and abdominal pain in chronic cannabis users. It…
Cannabinoids and Multiple Sclerosis: A Critical Analysis of Therapeutic Potentials and Safety Concerns
Abstract Multiple sclerosis (MS) is a complicated condition in which the immune system attacks myelinated axons in the central nervous…
An fMRI analysis of verbal and non-verbal working memory in people with a past history of opioid dependence
Abstract Introduction: Working memory describes the ability to maintain and manipulate information held in mind, and it is a fundamental…
Point estimation for adaptive trial designs II: Practical considerations and guidance
Abstract In adaptive clinical trials, the conventional end‐of‐trial point estimate of a treatment effect is prone to bias, that is,…
Association between serum Chlamydia trachomatis antibody levels and infertility among reproductive-aged women in the U.S.
Abstract Introduction: Chlamydia trachomatis infection, the most prevalent sexually transmitted bacterial infection worldwide, is a significant cause of infertility. Many…