Unraveling Chronic Pain: From Mechanisms and Risks to Diagnosis and Treatment
Abstract Chronic pain is a globally prevalent and complex condition, encompassing three primary subtypes, that is, nociceptive, neuropathic, and nociplastic,…
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Deltex E3 ubiquitin ligase 2 potentiates STING-mediated type I interferon response by K63-linked ubiquitination
Abstract Stimulator of interferon genes (STING) signaling, as a pivotal DNA-sensing mechanism, orchestrates antiviral and antitumor immunity through the induction…
A Cross-Sectional Survey of Cannabis Use and Utility Among Patients Experiencing Dizziness
Abstract Highlights: What are the main findings? What are the implications of the main findings? Abstract: Background/Objective: Dizziness is managed…
Reasons for Using Cannabis Among Adults in the United States: Associations with Demographics, Health Behaviors, Chronic Conditions, and Legal Status
Abstract Highlights: Public health relevance—How does this work relate to a public health issue? Public health significance—Why is this work…
Hemp Essential Oils as Novel Antioxidant and Bacteriostatic Agents in PLA-Based Packaging
Abstract Poly(lactic acid) (PLA) films containing two different hemp-derived essential oils (EOs), Carmagnola CS (Carm) and Futura 75 (Fut), at…
Plant-Derived Functional Ingredients in Pet Nutrition: Phytochemical Classification, Mechanisms, Efficacy, and Application in Dogs and Cats
Abstract Modern pet nutrition is evolving toward the use of phytochemical-rich, plant-derived ingredients that provide health benefits rather than basic…
Development and Validation of Quality of Life in Idiopathic Intracranial Hypertension (QOLIH) questionnaire
Abstract Background: Poor quality of life (QOL) has emerged as a key morbidity in patients with idiopathic intracranial hypertension (IIH).…
Natural Product-Derived Activity-Based and Affinity-Based Probes: Tools for Mechanism of Action Studies
Abstract Natural products have played a pivotal role in the history of drug discovery, yet mechanistic investigations have often posed…
Stellate Ganglion Block for the Management of Cannabis Use Disorder: A Case Series
Abstract Currently, there are no approved or consistently effective pharmacological treatments for managing cannabis use disorder. Three patients diagnosed with…
Muscular Dystrophy Muscle Preservation: A Comparative Systematic Review of Exercise and Cannabidiol (CBD) Interventions
Abstract Muscular dystrophy comprises a heterogeneous group of inherited neuromuscular disorders characterized by progressive muscle degeneration, weakness, and functional decline.…