Impact of cannabinoids on synapse markers in an SH-SY5Y cell culture model
Abstract Patients suffering from schizophrenic psychosis show reduced synaptic connectivity compared to healthy individuals, and often, the use of cannabis…
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Estrogen enhances the proliferation, migration, and invasion of papillary thyroid carcinoma via the ERα/KRT19 signaling axis
Abstract Background: Estrogen is thought to be the reason for the higher prevalence of papillary thyroid carcinoma (PTC) in fertile…
The oncogenic axis YAP/MYC/EZH2 impairs PTEN tumor suppression activity enhancing lung tumorigenicity
Abstract The tumor suppressor PTEN (phosphatase and tensin homolog deleted in chromosome 10) is genetically deleted or downregulated in many…
Substance abuse among new patients attending main government hospitals in Malaysia from 2018–2021: A comparison between before and during COVID-19 pandemic
Abstract Background: Substance abuse admission to health facilities following the pandemic is often met with challenges. COVID-19 is causing an…
Genomic structural equation modeling reveals latent phenotypes in the human cortex with distinct genetic architecture
Abstract Genetic contributions to human cortical structure manifest pervasive pleiotropy. This pleiotropy may be harnessed to identify unique genetically-informed parcellations…
Mechanisms of Cannabis Growth Promotion by Bacillus velezensis S141
Abstract Cannabis sativa L. has a variety of uses, including fiber production, food, oil, and medicine. In response to environmental…
The impact of cannabinoid receptor 1 absence on mouse liver mitochondria homeostasis: insight into mitochondrial unfolded protein response
Abstract Introduction: The contribution of Cannabinoid type 1 receptor (CB1) in mitochondrial energy transduction mechanisms and mitochondrial activities awaits deeper…
Temperature-Responsive Injectable Composite Hydrogels Based on Poly(N-Isopropylacrylamide), Chitosan, and Hemp-Derived Cellulose Nanocrystals
Abstract Injectable and temperature-responsive Poly(N-Isopropylacrylamide) (PNIPAAm)/Chitosan composite hydrogels reinforced with cellulose nanocrystals (CNCs) were successfully fabricated via photopolymerization. 0.1–3% (w/v)…
Case reports of identical twins with developmental and epileptic encephalopathy with STXBP1 gene mutations for whom different CBD supplementations were markedly effective
Abstract Identical twins with intractable epilepsy achieved seizure suppression with CBD. CBD products that proved effective in each patient differed,…
Cannabidiol (CBD) Protects Lung Endothelial Cells from Irradiation-Induced Oxidative Stress and Inflammation In Vitro and In Vivo
Abstract Radiotherapy remains a central pillar in the therapy of solid tumors, including lung cancer. However, the clinically applied radiation…