Spontaneous Coronary Artery Dissection in the Setting of Marijuana: A Case Report
Abstract This case report presents a detailed examination of spontaneous coronary artery dissection (SCAD) in a 61-year-old Middle Eastern male…
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A comprehensive review on phytochemicals in the treatment and prevention of pancreatic cancer: Focusing on their mechanism of action
Abstract Background and Aims: Pancreatic cancer develops in the normal tissues of the pancreas from malignant cells. The chance of…
Updates in Cancer Cachexia: Clinical Management and Pharmacologic Interventions
Abstract Simple Summary: Cancer cachexia (CC) is a complex syndrome requiring a multimodal approach. Although a universally accepted definition and…
Effects of CB1 receptor negative allosteric modulator Org27569 on oxycodone withdrawal symptoms in mice
Abstract Rationale/Objectives: Targeting cannabinoid receptor type 1 (CB1R) has shown promise for treating opioid withdrawal symptoms. This study aimed to…
Extraction, purification and in vitro assessment of the antioxidant and anti-inflammatory activity of policosanols from non-psychoactive Cannabis sativa L.
Abstract Policosanols (PCs) are bioactive compounds extracted from different natural waxes. In this work, the purification, characterization and assessment of…
Cannabidiol-Loaded Solid Lipid Nanoparticles Ameliorate the Inhibition of Proinflammatory Cytokines and Free Radicals in an In Vitro Inflammation-Induced Cell Model
Abstract Cannabidiol (CBD) is a non-psychoactive compound derived from Cannabis sativa. It has demonstrated promising effects in combating inflammation and…
Perinatal Tetrahydrocannabinol Compromises Maternal Care and Increases Litter Attrition in the Long–Evans Rat
Abstract The marijuana legalization trend in the U.S. will likely lead to increased use by younger adults during gestation and…
Investigating sex differences and age of onset in emotion regulation, executive functioning, and cannabis use in adolescents and young adults
Abstract Background: Young adults have historically high levels of cannabis use at a time which coincides with emotional and cognitive…
Cannabis oil extracts for chronic pain: what else can be learned from another structured prospective cohort?
Abstract In real world, cannabis oil extracts containing relatively low Δ9-tetrahydrocannabinol and cannabidiol doses demonstrated improvement in pain and related…
Genome-wide identification and analysis of ascorbate peroxidase (APX) gene family in hemp (Cannabis sativa L.) under various abiotic stresses
Abstract Ascorbate peroxidase (APX) plays a critical role in molecular mechanisms such as plant development and defense against abiotic stresses.…