Malnutrition in Substance Use Disorders: A Critical Issue in Their Treatment and Recovery
Abstract Substance use disorders (SUDs) are widely prevalent in many countries, with the highest rates observed in nicotine and alcohol…
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Cohort-based pan-cancer analysis and experimental studies reveal ISG15 gene as a novel biomarker for prognosis and immunotherapy efficacy prediction
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s00262-025-04026-y. Article type: Research Article Keywords: Interferon-stimulated gene ISG15,…
Evaluating the Thermal Conductivity of Hemp-Based Insulation
Abstract This study evaluates the thermal conductivity of hemp-based insulation materials, focusing on loose bulk mixtures of hemp fibre and…
The Role of Post-Translational Modifications in Necroptosis
Abstract Necroptosis, a distinct form of regulated necrosis implicated in various human pathologies, is orchestrated through sophisticated signaling pathways. During…
3D-Bioprinted Oil-Based Hydrogels: A Sustainable Approach for Bone and Dental Regeneration
Abstract Recent advancements in 3D bioprinting technology have transformed the development of complex tissue scaffolds, offering significant potential for applications…
Synthesis, Characterization, and Biological Effects of Chloro-Cathinones: Toxicity and Potential Neurological Impact
Abstract Cathinones, a class of synthetic new psychoactive substances (NPSs), continue to emerge and pose public threats. Government control efforts…
Promising high fidelity genetic markers for sexing Cannabis sativa seedlings
Abstract The uses of Cannabis sativa, a dioecious species with an XY sex chromosome system, are varying from fiber and…
A universal cannabinoid CB1 and CB2 receptor TR-FRET kinetic ligand-binding assay
Abstract Introduction: The kinetics of ligand binding to G protein-coupled receptors (GPCRs) is an important optimization parameter in drug discovery.…
Convergence of Cannabis and Psychosis on the Dopamine System
Abstract This cohort study investigates the association between cannabis and the midbrain dopamine pathway involved in psychosis. Authors: Jessica Ahrens,…
Pharmacokinetics of cannabidiol, (-)-trans-Δ9-tetrahydrocannabinol, and their oxidative metabolites after intravenous and oral administration of a cannabidiol-dominant full-spectrum hemp product to beagle dogs
Abstract Introduction: This study investigated the pharmacokinetics, safety, and tolerability of a full-spectrum CBD-dominant oil formulated in medium-chain triglycerides (MCT…