Case report: High-grade serous tubo-ovarian carcinoma with FGFR2::IQCG fusion and insights into targetability
Abstract FGFR2 fusion is one of the classes of emerging therapeutic targets of precision oncology and is observed in many…
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Lichen and Its Microbiome as an Untapped Source of Anti‐Biofilm Compounds
Abstract Lichen substances have been first described in the 1870s, and around 10 000 compounds have been isolated and characterized.…
Exploring the diversity of cannabis cannabinoid and non-cannabinoid compounds and their roles in Alzheimer’s disease: A review
Abstract Cannabis sativa is recognized for its chemical diversity and therapeutic potential, particularly in addressing neurodegenerative diseases such as Alzheimer’s…
Indigenous peoples as trustees of forests: a bio-socio-cultural approach to international law
Abstract Forests are an essential part of Mother Earth within the Earth system. Deforestation is a widespread practice due to…
Cannabis sativa extracts inhibit LDL oxidation and the formation of foam cells in vitro, acting as potential multi-step inhibitors of atherosclerosis development
Abstract Atherosclerotic disease is the leading cause of death world-wide. Our goal was to explore the effect of phytocannabinoids on…
Is nitrogen-modified atmosphere packaging a tool for retention of volatile terpenes and cannabinoids in stored Cannabis sativa inflorescence?
Abstract Supplementary Information: The online version contains supplementary material available at 10.1186/s42238-024-00253-9. Article type: Research Article Keywords: Aromatics, Cannabigerol, High…
Cytotoxicity and Immunomodulatory Effects of Cannabidiol on Canine PBMCs: A Study in LPS-Stimulated and Epileptic Dogs
Abstract Cannabidiol has gained attention owing to its potential anti-inflammatory and neuroprotective properties. This research examined cannabidiol’s cytotoxicity and its…
Cannabidiol-Loaded Lipid Nanoparticles Incorporated in Polyvinyl Alcohol and Sodium Alginate Hydrogel Scaffold for Enhancing Cell Migration and Accelerating Wound Healing
Abstract Chronic wounds represent a persistent clinical challenge due to prolonged inflammation and impaired tissue repair mechanisms. Cannabidiol (CBD), recognized…
Utilizing machine learning-based QSAR model to overcome standalone consensus docking limitation in beta-lactamase inhibitors screening: a proof-of-concept study
Abstract Supplementary Information: The online version contains supplementary material available at 10.1186/s13065-024-01324-x. Article type: Research Article Keywords: Molecular docking, Consensus…
Nucleus Accumbens Associated Protein 1 in Cancers—The Real Value
Abstract Malignant tumors are a leading cause of death worldwide, second only to cardiovascular disease. They occur in every population…