Case report: High-grade serous tubo-ovarian carcinoma with FGFR2::IQCG fusion and insights into targetability
Abstract FGFR2 fusion is one of the classes of emerging therapeutic targets of precision oncology and is observed in many…
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Lichen and Its Microbiome as an Untapped Source of Anti‐Biofilm Compounds
Abstract Lichen substances have been first described in the 1870s, and around 10 000 compounds have been isolated and characterized.…
Exploring the diversity of cannabis cannabinoid and non-cannabinoid compounds and their roles in Alzheimer’s disease: A review
Abstract Cannabis sativa is recognized for its chemical diversity and therapeutic potential, particularly in addressing neurodegenerative diseases such as Alzheimer’s…
Iron(ing) out parkinsonisms: The interplay of proteinopathy and ferroptosis in Parkinson’s disease and tau-related parkinsonisms
Abstract Parkinsonian syndromes are characterised by similar motor-related symptomology resulting from dopaminergic neuron damage. While Parkinson’s disease (PD) is the…
Treatment Strategies for Painful Pelvic Floor Conditions: A Focus on the Potential Benefits of Cannabidiol
Abstract Painful conditions of the pelvic floor include a set of disorders of the pelvic region, discreetly prevalent in the…
Newly developed genomic SSR markers revealed the population structure and genetic characteristics of abaca (Musa textilis Nee)
Abstract Abaca (Musa textilis Nee) is the primary source of manila hemp fiber, a vital industrial product for the country.…
The clinical and biochemical effectiveness and safety of cholic acid treatment for bile acid synthesis defects: a systematic review
Abstract Background: Bile acid synthesis defects (BASDs) can be severely disabling involving the liver and nervous system, potentially due to…
Cuproptosis: a promising new target for breast cancer therapy
Abstract Breast cancer (BC) is the leading cause of cancer-related mortality among women globally, affecting approximately one-quarter of all female…
Demographic Profiles, Etiological Spectrum, and Anatomical Locations of the Post-Hepatic Obstructive Jaundice in Adult Population in Hadhramout Region in Yemen
Abstract Background: Obstructive jaundice is a common health challenge in daily clinical practice caused by a heterogeneous group of benign…
Enhancing Greenhouse Efficiency: Integrating IoT and Reinforcement Learning for Optimized Climate Control
Abstract Automated systems, regulated by algorithmic protocols and predefined set-points for feedback control, require the oversight and fine tuning of…