Beyond the hype: a comprehensive exploration of CBD’s biological impacts and mechanisms of action
Abstract Background: Cannabidiol (CBD) is the primary non-psychoactive component of cannabis. Consumption of CBD is increasing rapidly as it is…
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Self-Assembled Cannabigerol-Based Nanoparticles: Design, Synthesis, and Antiproliferative Activity
Abstract Background/Objectives: Cannabigerol (CBG) is a non-psychoactive phytocannabinoid with significant therapeutic potential, showing emerging applications in drug delivery. This study…
The Regulatory Environment Surrounding Cannabis Medicines in the EU, the USA, and Australia
Abstract Background/Objectives: Recent evidence supporting the medicinal use of cannabis has brought significant regulatory changes regarding its legal status, cultivation,…
Utilization of Industrial Hemp Biomass Waste (I): Stability of Cannabidiol in Pre and Post- Encapsulation States
Abstract After cannabidiol was extracted from the hemp biomass using supercritical CO2 extraction, the residual could be utilized as a…
Cannabidiol-Loaded Retinal Organoid-Derived Extracellular Vesicles Protect Oxidatively Stressed ARPE-19 Cells
Abstract Background/Objectives: Age-related macular degeneration (AMD) is the third leading cause of irreversible blindness in elderly individuals aged over 50…
Effects of cannabidiol (CBD) treatment on age-related cognitive decline in C57 mice
Abstract Aging is associated with cognitive decline, and currently, there are no approved medications that can prevent these impairments. Recently,…
Assessing the Market Readiness for Medical Cannabis in Greece: A Qualitative Study of Patient Perspectives
Abstract Background: The introduction of medical cannabis in Greece marks a shift in healthcare policy, yet patient attitudes remain underexplored.…
Pharmacokinetic Prediction and Cytotoxicity of New Quercetin Derivatives
Abstract Quercetin (QUE) possesses various pharmacological properties; however, its low bioavailability and solubility hinder its beneficial effects. Enzymatic glycosylation has…
Antileishmanial Activities of Carvacrol Nanoencapsulate in Biopolymeric Nanoparticles
Abstract Visceral leishmaniasis (VL) is a neglected parasitic disease, and the first‐line treatments for VL include drugs that exhibit serious…
Elucidating the transcriptomic response of adult-derived mHypoA-2/12 mouse hypothalamic neuron cell line to cannabidiol (CBD) exposure
Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s13353-025-00970-8. Article type: Research Article Keywords: CBD, Hypothalamic neurons,…