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Research Article 2026CC BYCC BY allows this article to remain publicly readable here. Any reuse must still follow the recorded source terms.Free full text

Cannabidiol- and Celecoxib-Loaded Liposomes as a Strategy to Modulate Redox and Inflammatory Signaling in High-Grade Glioma: A Preliminary In Vivo Study.

Anna Rybarczyk, Aleksandra Majchrzak-Celińska, Ludwika Piwowarczyk, Szymon Tomczak, Dorota Wronka, Anna Karlik +2 more

Inflammation contributes to the rapid progression of high-grade gliomas, indicating that anti-inflammatory strategies targeting NF-κB signaling may offer therapeutic benefit. Cannabidiol (CBD) and celecoxib (CELE) are hydrophobic pharmacological agents whose formulation in lipid carriers may support their combined biological evaluation. In this proof-of-concept study, we investigated liposomal formulations contain…

high-grade glioma cannabidiol (CBD)celecoxib (CELE)nanoformulations liposomes combinatorial treatment NF-κB pathway

International Journal of Molecular Sciences PubMed Central Open Access↗

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