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Research Article 2024CC BYFree full text

Polarization of HIV-1- and CMV-Specific IL-17-Producing T Cells among People with HIV under Antiretroviral Therapy with Cannabis and/or Cocaine Usage.

Fernanda de Oliveira Feitosa de Castro, Adriana Oliveira Guilarde, Luiz Carlos Silva Souza, Regyane Ferreira Guimarães, Ana Joaquina Cohen Serique Pereira, Pedro Roosevelt Torres Romão +5 more

Objective This study evaluated the influence of cannabis and/or cocaine use in human immunodeficiency virus (HIV)- and cytomegalovirus (CMV)-specific T-cell responses of people with HIV (PWH). Results There was a higher percentage of IL-17-producing HIV-Gag-specific CD8+ T-cells in all drug users than that in PWH non-drug users. Stratifying the drug-user groups, increased percentages of IL-17-producing HIV-Gag-spe…

Pharmaceuticals Europe PMC

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Research Article 2024CC BYFree full text

Application of LC-MS/MS for the Identification of Drugs of Abuse in Driver's License Regranting Procedures.

Roberta Tittarelli, Lucrezia Stefani, Leonardo Romani, Federico Mineo, Francesca Vernich, Giulio Mannocchi +6 more

Background: Drugged driving is associated with an increased risk of road accidents worldwide. In Italy, driving under the influence (DUI) of alcohol and drugs is a reason for driving disqualification or revocation of the driving license. Drivers charged with driving under the influence of alcohol and drugs must attend a Local Medical Commission (LMC) to undergo mandatory examinations to regain the suspended licens…

Pharmaceuticals Europe PMC