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Research Article 2022-12-17CC BYFree full text

Sustained reductions in life-threatening invasive bacterial diseases during the first two years of the COVID-19 pandemic: analyses of prospective surveillance data from 30 countries participating in the IRIS Consortium

David Shaw, Raquel Abad, Zahin Amin-Chowdhury, Adriana Bautista, Desiree Bennett, Karen Broughton +94 more

BackgroundThe Invasive Respiratory Infection Surveillance (IRIS) Consortium was established to assess the impact of the COVID-19 pandemic on invasive diseases caused by Streptococcus pneumoniae, Haemophilus influenzae, Neisseria meningitidis and Streptococcus agalactiae. Here we analyse the incidence and distribution of disease during the first two years of the pandemic. MethodsLaboratories in 30 countries/territo…

medRxiv medRxiv

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Research Article 2019-02-26CC BYFree full text

Genomic surveillance for hypervirulence and multi-drug resistance in invasive Klebsiella pneumoniae from south and southeast Asia.

Kelly L Wyres, To N T Nguyen, Margaret M C Lam, Louise M Judd, Nguyen van Vinh Chau, David A B Dance +14 more

BackgroundK. pneumoniae is a leading cause of blood stream infection (BSI). Strains producing extended spectrum beta-lactamases (ESBLs) or carbapenemases are considered global priority pathogens for which new treatment and prevention strategies are urgently required, due to severely limited therapeutic options. South and Southeast Asia are major hubs for antimicrobial resistant (AMR) K. pneumoniae, and also for th…

bioRxiv bioRxiv

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