Readable research linked to original sources

Articles

Browse normalized, publication-ready research with direct links to its evidence and source.

2 articles

Newest first

Research Article 2025-11-21CC BYFree full text

The effect of BCG vaccination on adult mortality during the COVID-19 pandemic: a meta-analysis of randomised controlled trials

Frederik Schaltz-Buchholzer, Nigel Curtis, Andreas H. Diacon, Evangelos J. Giamarellos-Bourboulis, Antigone Kotsaki, Anne Marie Rosendahl Madsen +11 more

ObjectivesBacillus Calmette-Guerin (BCG), similar to some other live vaccines, may offer partial protection against unrelated infections. During the COVID-19 pandemic, several trials tested whether BCG provides protection against COVID-19. DesignMeta-analysis of randomised placebo-controlled trials which provided mortality data. SettingHigh-income settings as well as low- and middle-income settings (LMICs). Partic…

medRxiv medRxiv

Open article record in new tab ↗

Research Article 2024-06-11CC BYFree full text

Safety, Effectiveness and Immunogenicity of heterologous mRNA-1273 Boost after Prime with Ad26.COV2.S among Healthcare Workers in South Africa: the single-arm, open-label, Phase 3 SHERPA Study

Nigel Garrett, Tarylee Reddy, Nonhlanhla Yende-Zuma, Azwidhwi Takalani, Kubashni Woeber, Annie Bodenstein +51 more

Given limited data on safety and effectiveness of heterologous COVID-19 vaccine boosting in lower income, high-HIV prevalence settings, we evaluated a mRNA-1273 boost after Ad26.COV2.S priming in South Africa. SHERPA was a single-arm, open-label, phase 3 study nested in the Sisonke implementation trial of 500000 healthcare workers (HCWs). Sisonke participants were offered mRNA-1273 boosters between May and Novembe…

medRxiv medRxiv

Open article record in new tab ↗