Pan-cancer analyses of synonymous mutations based on tissue-specific codon optimality

Keywords: Synonymous mutations, Codon optimality, Cell cycle, DNA damage repair deficiency, Cancer Authors: Xia Ran, Jinyuan Xiao, Fang Cheng, Tao Wang, Huajing Teng, Zhongsheng Sun Affiliations: Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing 100101, China; CAS Center for Excellence in Biotic Interactions, University of Chinese Academy of Sciences, Beijing 100049, China; Institute of Genomic Medicine, Wenzhou Medical University, Wenzhou 325000, China; Center for Medical Genetics & Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central