Histological and Biochemical Alterations in the Superior Colliculus and Lateral Geniculate Nucleus of Juvenile Rats Following Prenatal Exposure to Marijuana Smoke

Abstract Introduction: Prenatal exposure to Marijuana (MJN) has been associated with various brain deficits. The main activity in marijuana, Δ9-Tetrahydrocannabinol (THC), crosses the placenta and affects fetal brain development. Despite this, marijuana remains a commonly abused substance among pregnant women. The current study examined the histological and biochemical changes in the Superior Colliculus (SC) and Lateral Geniculate Nucleus (LGN) in rat brains prenatally exposed to marijuana. Methods: Four groups of pregnant rats (n=5 rats/group) were exposed to the smoke of