Association of CD2AP neuronal deposits with Braak neurofibrillary stage in Alzheimer’s disease
Abstract Genome‐wide association studies have described several genes as genetic susceptibility loci for Alzheimer’s disease (AD). Among them, CD2AP encodes CD2‐associated protein, a scaffold protein implicated in dynamic actin remodeling and membrane trafficking during endocytosis and cytokinesis. Although a clear link between CD2AP defects and glomerular pathology has been described, little is known about the function of CD2AP in the brain. The aim of this study was to analyze the distribution of CD2AP in the AD brain and its potential
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