A Pan-Cancer Analysis of the Role of Selenoprotein P mRNA in Tumorigenesis

Abstract Background: Selenium (Se) exhibits its anti-carcinogenic properties by regulating the redox system. However, the relationship between selenoprotein P (SeP), mRNA (SELENOP mRNA) and tumorigenesis remains unclear. Plasma SeP transports Se to various target tissues and has antioxidant characteristics. The present study aimed to explore the multifaceted pan-cancer properties of SELENOP in terms of its tissue-specific expression, prognostic value, immune function, and signaling pathway enrichment. Patients and Methods: The expression profile of SELENOP was determined in 33 tumor types and