Indocyanine Green Clearance Test to Evaluate Liver Function in Rat Model of Extrahepatic Biliary Atresia

Abstract Background: Indocyanine green clearance test (ICG-K) has been shown as a sensitive marker of liver function in patients with cirrhosis. However, its role in the assessment of liver function in children with biliary atresia is not well established. The present study was undertaken to evaluate the ICG-K in an experimental model of cholangitis and partial biliary obstruction. Materials and Methods: Thirty albino rats were divided into 3 groups of 10 each. After exploration under anesthesia, a vial of OK-432