Cannabis Use Disorder and Postoperative Pain: Elevated Analgesic Requirements After Surgical Repair of Hand Fractures

Abstract Background: Cannabis is one of the most widely used psychoactive substances in the United States, yet clinical research on its impact in surgical settings remains limited. Despite its growing use and perceived analgesic potential, the effects of cannabis use disorder (CUD) on postoperative pain management are poorly understood. This study investigates whether patients with CUD exhibit increased postoperative analgesic requirements following surgical treatment of hand fractures. Methods: We conducted a retrospective cohort study using TriNetX, a global federated health