Bioinformatics analysis identifies AURKB as a prognostic biomarker across multiple human cancers
Abstract Background: Cancer is a major global health issue. Aurora kinase B (AURKB) is known to regulate cell division and linked to poor prognosis in some cancers, but its role across all cancer types is unclear. Objective: The goal of this study is to examine how AURKB expression, epigenetic regulation, and immune cell infiltration relate to its potential as a prognostic biomarker. Methods: We conducted a comprehensive analysis of transcriptomic and clinical data from TCGA, HPA, and CCLE to assess
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