RERE-AS1 as a regulator of immune modulation and therapeutic response in breast cancer

Abstract Background and aims: Breast cancer (BRCA) remains one of the most prevalent malignancies and a major threat to women’s health worldwide. The biological role and mechanistic basis of the long non-coding RNA (lncRNA) RERE-AS1 in BRCA remain unclear. Methods: Clinical and RNA sequencing data from BRCA patients were analyzed to determine RERE-AS1 expression levels. RNA fluorescence in situ hybridization (FISH) was used to visualize its distribution in tumor tissues. Functional assays were conducted in MCF-7 and T47D cells to