Exploring ASPN as a pan-cancer biomarker with a focus on gastric cancer

Abstract Background: Cancer remains a leading cause of mortality worldwide, posing a serious threat to public health. The ASPN protein has emerged as a key player in certain cancers; however, its precise mechanisms and regulatory roles are still not well-defined. Methods: We explored the expression of ASPN and its prognostic significance across various cancers. Functional enrichment analyses were conducted using the Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Ontology (GO). The association between ASPN expression and factors including