Assessment of uteroplacental perfusion with 3D power Doppler for the early prediction of pre-eclampsia: a systematic review and meta-analysis

Abstract Background: The assessment of uteroplacental perfusion to identify the risk of pre-eclampsia (PE) is essential but challenging. We conducted a meta-analysis to evaluate the value of vascularization indices (VIs) derived from three-dimensional power Doppler (3D-PD) for the early prediction of PE. Methods: We conducted a search of the PubMed, Web of Science, Cochrane Library, and Embase databases to retrieve eligible studies, published up to October 22, 2024. Studies were considered eligible for inclusion in the meta-analysis if they assessed