SMPD2 affects the prognosis of cancer patients by mediating lipid metabolism and the immune microenvironment

Abstract Supplementary Information: The online version contains supplementary material available at 10.1007/s12672-025-03553-5. Article type: Research Article Keywords: SMPD2, Biomarker, Immune cell infiltration, Pan-cancer, Prognosis Authors: Qing-Yan Li, Jia-Ming Huang, Xiang Yuan, Hui-Long Guo, Wei Zhang, Yu-Chuan Chen, Yi-yi Li, Ze Song Affiliations: https://ror.org/00rfd5b88grid.511083.e0000 0004 7671 2506Emergency and Disaster Medicine Center, The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, 518107 Guangdong Province China; Department of Hepatobiliary and Gastrointestinal Surgery, Shenzhen Guangming District People’s Hospital, Shenzhen, China; https://ror.org/01vjw4z39grid.284723.80000 0000 8877 7471Department