Eugenia brasiliensis: Analysis of the Chemical Profile and Evaluation of Cytotoxic Potential

Abstract This work evaluated the antiproliferative potential of Eugenia brasiliensis leaf extracts against the HeLa cervical cancer cell line. The extracts were prepared by maceration using hexane (EBH), dichloromethane (EBD), and ethyl acetate (EBAE), and they were evaluated for their antiproliferative potential through a 3‐4,5‐dimethyl‐thiazol‐2‐yl‐2,5‐diphenyltetrazoliumbromide (MTT) assay in the cervical cancer cell culture (HeLa cell line) and a non‐cancer cell line (NIH‐3T3). EBH, EBD, and EBAE were cytotoxic in HeLa cells, with 50% inhibition concentration (IC50) = 97.59, 31.03, and