Clinical and computed tomography characteristics of high-risk periampullary diverticulum

Abstract Background: Periampullary diverticulum (PAD) is a common acquired extraluminal outpouching of duodenal mucosa and is often clinically overlooked. When complicated by biliary-pancreatic stones or inflammation, PAD may lead to severe biliary-pancreatic complications. Although endoscopic retrograde cholangiopancreatography (ERCP) is currently regarded as the gold standard for PAD diagnosis, its invasive nature and other limitations have led to computed tomography (CT) being increasingly preferred as the first-line imaging modality. However, the correlation between imaging features and clinical manifestations remains unclear for