Ras and Rab interactor 3 as a prognostic biomarker and its impact on immune cell infiltration in cancer

Abstract RIN3, a member of the RIN protein family, plays a pivotal role in disease progression by modulating Rab5 activity and influencing cell signaling pathways, which in turn affect tumor proliferation and migration. Our study systematically examined RIN3 expression in various tumor types using data from TCGA, GTEx, and single-cell RNA sequencing of 77 tumor types in the TISCH database, aiming to clarify its potential role in cancer. We evaluated the association between RIN3 levels and patient survival via univariate