Functional Dyspepsia and Its Subgroups: Prevalence and Impact in the Rome IV Global Epidemiology Study

Abstract Background: Functional dyspepsia (FD) is one of the most common disorders of gut–brain interaction (DGBI). Varying reported population prevalences probably reflect different definitions and methodological approaches. Aim: To study the prevalence and impact of FD and its subgroups in an internet survey. Methods: A total of 54,127 respondents from 26 countries completed the survey including the Rome IV diagnostic questionnaire, Patient Health Questionnaire‐4 (PHQ‐4), PHQ‐12, PROMIS Global‐10, demographics, and medical history. Respondents reporting a history of relevant organic disease,