PKM2 modulates chemotherapy sensitivity by regulating autophagy and predicts the prognosis and immunity in pancancer

Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-025-96562-x. Article type: Research Article Keywords: PKM2; prognosis, Tumor microenvironment, Immune cell infiltration, Immunotherapy, Chemotherapy, Pan-cancer, Oesophageal cancer, Immunology, Health care Authors: Haosheng Zheng, Jian Tan, Fei Qin, Yuzhen Zheng, Xingping Yang, Zui Liu, Weijie Cai, Xianyu Qin, Hongying Liao Affiliations: https://ror.org/0064kty71grid.12981.330000 0001 2360 039XDepartment of Thoracic Surgery, Thoracic Cancer Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510655 Guangdong China; https://ror.org/0064kty71grid.12981.330000 0001 2360 039XBiomedical Innovation Center, The