Nanotechnology-leveraged CRISPR/Cas systems: icebreaking in trace cancer-related nucleic acids biosensing

Abstract Graphical Abstract: Supplementary Information: The online version contains supplementary material available at 10.1186/s12943-024-02222-5. Article type: Review Article Keywords: Cancer biomarkers, Nucleic acids, CRISPR/Cas, Nanotechnology, Ultra-sensitive detection Authors: Weipan Peng, Mengting Shi, Bin Hu, Jingyu Jia, Xinyue Li, Nan Wang, Shuli Man, Shengying Ye, Long Ma Affiliations: https://ror.org/018rbtf37grid.413109.e0000 0000 9735 6249State Key Laboratory of Food Nutrition and Safety, Key Laboratory of Industrial Microbiology, Tianjin Key Laboratory of Industry Microbiology, International China International Science and Technology Cooperation Base of Food Nutrition/Safety