WDR77 in Pan-Cancer: Revealing expression patterns, genetic insights, and functional roles across diverse tumor types, with a spotlight on colorectal cancer

Abstract Conducted a comprehensive pan-cancer analysis of WDR77, revealing diverse expression patterns and genetic alterations across multiple cancer types. Explored the relationship between WDR77 and the tumor immune microenvironment, uncovering potential immunosuppressive effects in certain cancers. Identified significant overexpression of WDR77 in colorectal cancer (CRC), linking it to enhanced cell proliferation and potential oncogenic roles. Article type: Research Article Keywords: WDR77, Pan-cancer, Colorectal cancer, Tumor microenvironment, Proliferation Authors: Yan Wang, Qihui Wu, Jiaxin Liu, Xuan Wang, Jialing Xie, Xiaodan Fu,