A comprehensive prognostic and immunological implications of PFKP in pan-cancer

Abstract Background: Phosphofructokinase P (PFKP) is a key rate-limiting enzyme in glycolysis, playing a crucial role in various pathophysiological processes. However, its specific function in tumors remains unclear. This study aims to evaluate the expression and specific role of PFKP across multiple tumor types (Pan-cancer) and to explore its potential clinical significance as a therapeutic target in cancer treatment. Methods: We analyzed the expression of PFKP, immune cell infiltration, and patient prognosis across various cancers using data from the Cancer