The role of mitochondria-related lncRNAs in characterizing the immune landscape and supervising the prognosis of osteosarcoma

Abstract We investigated the co-expression network of mitochondria-related genes and lncRNAs. An accurate mitochondria-related lncRNA signature is proposed for osteosarcoma. This lncRNA signature facilitates prognostic evaluation in osteosarcoma. This lncRNA signature effectively predicts the immune landscape in osteosarcoma. We highlight the multifaceted role of core mitochondria-related lncRNAs in pan-cancer. Article type: Research Article Keywords: Osteosarcoma, lncRNA, Mitochondria, Immune infiltration, Personal treatment Authors: Yiming Zhang, Nan Ru, Zhaowen Xue, Wenyi Gan, Ruilin Pan, Zelin Wu, Zihang Chen, Huajun Wang, Xiaofei Zheng