Off-label use of cannabidiol in genetic epileptic and developmental encephalopathies: A case report

Abstract Cannabidiol exerts also clinical beneficial non-seizure outocomes. Cannabidiol should be considered in other developmental epileptic encephalopathies. Cannabidiol presents antiepileptic, neuroprotective and anti-inflammatory effect. Article type: Case Report Keywords: Developmental epileptic encephalopathy, Quality of life, Cannabidiol, Epilepsy, Drug-resistance Authors: Elisa Mannini, Francesco Misirocchi, Stefania Lazzari, Giulia Balella, Dario Bottignole, Maddalena Frapporti, Lucia Zinno, Irene Florindo, Liborio Parrino, Carlotta Mutti Affiliations: Neurology Unit, Department of General and Specialized Medicine, Parma University Hospital, Parma, Italy; Interdepartmental Centre for Sleep Medicine, University of