Design and implementation of PharMe: a mobile application to return pharmacogenomic test results to patients

Abstract Objective: Pharmacogenomics can optimize therapeutic outcomes while minimizing adverse events. However, the lack of trained healthcare professionals has impeded its widespread adoption. Current patient-facing applications are either institution-specific or vary significantly in their coverage of genetic variants, interpretation guidelines, and data privacy protection. To address these shortcomings, we developed PharMe. Materials and Methods: All components were developed through co-design; experts created patient-friendly content in English from Clinical Pharmacogenomics Implementation Consortium and Food and Drug Administration guidelines. Results: PharMe returns