Integrated pan cancer analysis with breast cancer validation identifies SEC13 homolog as prognostic biomarker and immunotherapy target

Abstract Supplementary Information: The online version contains supplementary material available at 10.1038/s41598-026-52775-2. Article type: Research Article Keywords: Pan-cancer, Prognosis, Diagnosis, Tumor immunity, Methylation, Biomarkers, Cancer, Computational biology and bioinformatics, Oncology Authors: Haojie Fu, Jiawei Zhao, Yiyang Wang, Yongxiang Li, Haocong Li, Reyima Geni, Boen Sun, Chenming Guo Affiliations: https://ror.org/02qx1ae98grid.412631.3Department of Breast Surgery, Center of Digestive and Vascular, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China; https://ror.org/01p455v08grid.13394.3c0000 0004 1799 3993Department of Clinical Medicine, Xinjiang Medical University, Urumqi, China; https://ror.org/02qx1ae98grid.412631.3State